Critical Role of Hematological and Hematopoietic Tissue Evaluations in Aquatic Toxicology

Document Type : Original Article

Authors

1 Food Hygiene and Aquatic Animal department,Faculty of Veterinary Medicine, Semnan University, Semnan, Iran

2 Clinical science department, Faculty of Veterinary Medicine,Semnan University, Semnan, Iran

10.22075/jvlr.2025.36330.1144

Abstract

Hematological assessment in fish is widely recognized as a standard approach to evaluate their physiological status, primarily involving measurements of red blood cells, white blood cells, and platelets per unit volume of blood. This method serves as a fundamental tool for detecting the impact of various organic and inorganic substances on fish health and is often supplemented by biochemical analyses and histopathological evaluations. Its major advantages include low cost and minimal need for complex laboratory equipment. However, the accuracy of hematological analyses is largely influenced by the skill and experience of the examiner. To enhance the reliability of standard hematological assessments, it is recommended to also evaluate the cellular composition and functional activity of hematopoietic tissue. Despite its importance, limited information is available regarding the effects of xenobiotics (foreign chemical compounds) on the cellular structure of the anterior kidney hematopoietic tissue in fish, underscoring the need for additional research. Therefore, the combined application of hematological and hematopoietic analyses can provide a more comprehensive and precise evaluation of toxic substances’ impacts on fish health.

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