Comprehensive study of the epidemiology of brucellosis in humans and animals in the Khorasan region (Iran)

Document Type : Original Article

Authors

1 Department of Pathobiology, Faculty of Veterinary Medicine, Semnan University, Semnan, Iran

2 Bachelor of Veterinary Laboratory Sciences, Faculty of Veterinary Medicine, Semnan University, Iran.

Abstract

Brucellosis is a zeonosis and endemic disease in Iran, for accurate planning to control and eradicate the disease, it is necessary to study and investigate the epidemiological conditions of the region. The present study was carried out with the aim of investigating the epidemiology of brucellosis in the human and livestock populations of the Khorasan region (Iran). In this descriptive cross-sectional study, all studies related to human and animal brucellosis in three provinces of Khorasan region were reviewed. The results show that the prevalence of human brucellosis in the Khorasan region has increased significantly in recent years compared to a decade ago, with the prevalence of human brucellosis in Razavi, South and North Khorasan in 2009 being 25.41, 21.42 and 11.72 per 100,000 population respectively, reaching 78, 37 and 33 per 100,000 population respectively in 2020. Overall, the average prevalence of human brucellosis in the entire Khorasan region increased from 19.51 per 100 000 population in 2009 to 49 per 100 000 population in 2020. The prevalence of brucellosis in the region is also 0.56. % in cattle, 3.4% in small ruminants and 2.5% in horses. Epidemiological study of brucellosis in Khorasan region shows that the prevalence of brucellosis in the region is increasing, so the policy of brucellosis control should be reviewed and serious measures should be taken in this regard.
 
 

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References

Abedi, F., Salguqie, F., & Alemzadeh, E. (2022). Brucellosis in Herat Province, Afghanistan: Epidemiological Status and Risk Factors. Shiraz E-Medical Journal, 23.(4)
Akbarian, Z., Ziay, G., Schauwers, W., Noormal, B., Saeed, I., Qanee, A. H., Shahab, Z., Dennison, T., Dohoo, I., & Jackson, R. (2015). Brucellosis and Coxiella burnetii Infection in Householders and Their Animals in Secure Villages in Herat Province, Afghanistan: A Cross-Sectional Study. (1935-2735 (Electronic)).
Al Dahouk, S., Sprague Ld Fau - Neubauer, H., & Neubauer, H. (2013). New developments in the diagnostic procedures for zoonotic brucellosis in humans. (0253-1933 (Print)).
Blasco, J. A.-O., Moreno, E. A.-O., Muñoz, P. A.-O., Conde-Álvarez, R. A.-O., & Moriyón, I. A.-O. (2023). A review of three decades of use of the cattle brucellosis rough vaccine Brucella abortus RB51: myths and facts. (1746-6148 (Electronic)).
Bokaie, S., Sharifi, L., & Alizadeh, H. (2008). Epidemiological survey of brucellosis in human and animals in Birjand, east of Iran.
Dadar, M., Shahali, Y., & Fakhri, Y. (2021). Brucellosis in Iranian livestock: A meta-epidemiological study. Microbial Pathogenesis, 155, 104921.
Etemadi, A., Moniri, R., Saffari, M., Akbari, H., Alamian, S., & Behrozikhah, A. M.(2020). Epidemiological, molecular characterization and risk factors of human brucellosis in Iran. Asian Pacific Journal of Tropical Medicine, 13(4), 169-175.
Godfroid, J., Scholz, H.C., Barbier, T., Nicolas, C., Wattiau, P., Fretin, D., Whatmore, A.M., Cloeckaert, A., Blasco, J.M., Moriyon, I., Saegerman, C., Muma, J.B., Al Dahouk, S., Neubauer, H., Letesson, J.J., 2011. Brucellosis at the animal/ecosystem/human interface at the beginning of the 21st century. Preventive veterinary medicine. 102, 118-131.
Hashtarkhani, S. (2017). Epidemiological and clinical characteristics of human brucellosis in Razavi Khorasan proivince and important risk factors in the years 2008 to 2013. Medical Technologies Journal, 1(4), 108-108.
Kashfi, M., Hatamian, N., & Rakhshani, T. (2018). Epidemiological study of the brucellosis in Iran, andimeshk, 2001-2016. Journal of Health Sciences & Surveillance System, 6(1), 23-28.
Lotfi, Z., Pourmahdi Borujeni, M., Ghorbanpoor, M., & Ghadrdan Mashhadi, A. R. (2022). Seroprevalence and risk factors of brucellosis in Arabian horses. Veterinary Medicine and Science, 8(3), 1056-1064.
Moreno, E., Cloeckaert, A., & Moriyón, I. (2002). Brucella evolution and taxonomy. Veterinary microbiology, 90(1-4), 209–227. https://doi.org/10.1016/s0378-1135(02)00210-9
Norouzinezhad, F., Erfani, H., Norouzinejad, A., Kaveh, F., & Ghaffari, F. (2020). Epidemiology of human brucellosis (Malta fever) in Lorestan province during 2009-2017. Quarterly Journal of Caspian Health and Aging, 5(2), 66-79.
Rahimi, H., Kafshdouzan, K., Staji, H., & Kakolvand, Z. (2023). Epidemiological investigation of animal brucellosis in Lorestan province. Journal of Veterinary Laboratory Research, 15(1), 13-20.
Rahimi, H., Rashidian, E., Shams, N., & Jaydari, A. (2022). Multiple Locus Variable-Number Tandem Repeat Analysis Genotyping of Human Brucella melitensis Isolates from West of Iran. Journal of Advanced Biomedical Sciences.
Rahimi, H., Tukmechi, A., & Rashidian, E. (2023). Genetic diversity of Brucella melitensis isolates from sheep and goat milk in Iran. Veterinary Research Forum.
Rahimi, H., Tukmechi, A., Rashidian, E., 2020. Use of touch-down polymerase chain reaction to enhance the sensitivity of Brucella melitensis detection in raw milk. Anim. Biotechnol. 1–6. https://doi.org/10.1080/10495398.2020.1777149.,
Ramezani, H. A. R., Riabi, H. R. A., & Razmara, H. (2017). Epidemiological Feature of the Human Brucellosis Prevalence in People in Southern Cities of Khorasan Razavi, Iran. Zahedan Journal of Research in Medical Sciences, 19.(4)
Rostami, S., Rashidian, E., Jaydari, A., & Rahimi, H. (2023). Investigation of the Proportion of Brucella abortus and Brucella melitensis in Sheep and Goat Milk. Veterinary Medicine International, 2023(1), 6751152.
Sadooghi, N., Alamian, S., Moghadam, H. G., Yazdanmanesh, M., & Dadar, M. (2024). Serological and bacterial prevalence of Brucella spp. in suspected patients: a risk factor analysis in North Khorasan, Iran. Iranian Journal of Microbiology, 16(5), 639.
Shirzadi, M. R., Mohammadi, P., Moradi, G., Goodarzi, E., Khazaei, S., Moayed, L., & Khazaei, Z. (2021). The incidence and geographical distribution of brucellosis in Iran using geographic information system and prediction of its incidence in 2021. Journal of preventive medicine and hygiene, 62(3), E635.
Suresh, K. P., Patil, S. S., Nayak, A., Dhanze, H., Rajamani, S., Shivamallu, C., Cull, C. A., & Amachawadi, R. G. (2022). Prevalence of brucellosis in livestock of African and Asian continents: A systematic review and meta-analysis. Frontiers in Veterinary Science, 9, 923657.
Tahamtan, Y., Namavari, M. M., Mohammadi, G., & Jula, G. M. (2010). Prevalence of brucellosis in horse north-east of Iran. Journal of Equine Veterinary Science, 30(7), 376-378.
Tahmasebi, R., Jaydari, A., Shams, N., & Rahimi, H. (2022). Genomic detection of Brucella abortus in milk obtained from farms in Lorestan province using PCR method. Iranian Journal of Medical Microbiology, 16(5), 479-484.
Taleski, V., Zerva, L., Kantardjiev, T., Cvetnic, Z., Erski-Biljic, M., Nikolovski, B., Bosnjakovski, J., Katalinic-Jankovic, V., Panteliadou, A., & Stojkoski, S. (2002). An overview of the epidemiology and epizootology of brucellosis in selected countries of Central and Southeast Europe. Veterinary microbiology, 90(1-4), 147-155.
Whatmore, A. M., Davison, N., Cloeckaert, A., Al Dahouk, S., Zygmunt, M. S., Brew, S. D., Perrett, L. L., Koylass, M. S., Vergnaud, G., & Quance, C. (2014). Brucella papionis sp. nov., isolated from baboons (Papio spp.). International journal of systematic and evolutionary microbiology, 64(Pt_12), 4120-4128.
Zeinali, M., Doosti, S., Amiri, B., Gouya, M. M., & Godwin, G. N. (2022). Trends in the epidemiology of brucellosis cases in Iran during the last decade. Iranian Journal of Public Health, 51(12), 2791.
Zowghi, E., Ebadi, A., & Yarahmadi, M. (2008). Isolation and identification of Brucella organisms in Iran. Archives of Clinical Infectious Diseases, 3(4), 185-188.
 
 

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