Effect of Electromagnetic Field on Male Diabetic Bulb/C Mice Induced by Streptozocin (STZ)

Abstract

  Abstract:  D iabetes mellitus is one of the wide spreading endocrine diseases and its prevalent is increasing in human societies based on foreseen on style of modern life and nutrition habits. Use of Electromagnetic Field in preventing and treating diseases such as, pain relief healing ulcers and nervous system disorders has been recently examined as a medication substitute. In this investigate STZ-induced diabetic Balb/c mice were used. These animals were divided in six groups containing six mice in each group. Group 1 control, group 2 using insulin, group 3 using metformin, groups 4, 5, and 6 putting in electromagnetic field with 25, 50 and 100 Hz frequency and 250 µT intensity, respectively 45 minute daily for two weeks. Results were analyzed by Nonparametric Statistic (kruskal-wallis and U-mann withney) Test.   Results showed that the level of blood glucose for control group was 130 ± 4.7 mg/dl and the mean level of blood glucose for other groups after being diabetic and before treatment was 181 ± 10 mg/dl. The level of blood glucose for groups 2 – 6 after treatment were 162 ± 3.14, 165 ± 3.7, 141 ± 13.6, 165 ± 14.2, 169 ± 9.5 mg/dl, respectively.   In conclusion, the data indicated that a magnetic field with a frequency of 25 Hz and a field intensity of 250 m T produced the highest decreasing effect on blood sugar level (p

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